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Whether you're a surgeon interested in clinical collaboration, or an industry partner exploring strategic partnerships, we welcome conversations with stakeholders who share our aim to reduce subsidence complications.

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OptimalPSI AG
Picassoplatz 4
4052 Basel, Switzerland

info@optimalpsi.com

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Patient-specific, optimized spinal fusion implants. An official ETH Zürich spin-off.

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* In-Silico medical device testing: Smit et al. (2024). Frontiers in Bioengineering and Biotechnology, 12, 1347961.

** Pre-clinical computational modeling: Smit et al. (2024). Journal of Mechanical Behavior of Biomedical Materials, 159, 106695.

*** Ex-vivo biomechanical testing: Du et al. (2026). NASSJ, 26, 100890.

¹ Parisien et al. (2022). Subsidence of Spinal Fusion Cages: A Systematic Review. Table 6. Occurrence of subsidence per TLIF method considering >2 mm migration of the cage in the endplate.

² Carlson et al. (2020). Prevalence of osteoporosis and osteopenia diagnosed using quantitative CT in 296 consecutive lumbar fusion patients.

³ Godolias et al. (2023). Cage subsidence — A multifactorial matter!

Published clinical literature references available upon request.

OptimalPSI's patient-specific optimized TLIF implants are investigational. They have not been cleared or approved by the U.S. Food and Drug Administration (FDA) and do not hold CE marking. They are not available for sale in any market. Statements regarding performance are based on pre-clinical data; clinical performance has not been established.